Thermography

 

Principle

 

Thermography, or digital infra red thermal imaging (DITI), is a type of infra red (IR) imaging. Thermographic cameras detect IR radiation (roughly 0.9-14µm) and produce images of the radiating body. Since infrared radiation is emitted by all objects based on their temperature, according to the laws of (black body) electromagnetic radiation (see Stefan-Boltzmann Law and Wien’s displacement law). Thermography makes it possible to "see" one's environment with or without visible illumination. The amount of radiation emitted by an object increases with temperature. Therefore thermography allows one to see variations in temperature, hence the name. An infrared scanning device is used to convert infrared radiation emitted from the object surface into electrical impulses that are visualized in color on a monitor. This visual image graphically maps the surface temperature and is referred to as a thermogram. With a thermographic camera warm objects stand out well against cooler backgrounds. Humans and other warm-blooded animals become easily visible against the environment day or night, hence historically its extensive use can be ascribed to military and security services.

 

Medical DITI is a noninvasive diagnostic technique that allows the examiner to visualize and quantify changes in skin surface temperature. Since there is a high degree of thermal symmetry in the normal body, subtle abnormal temperature asymmetry's can be easily identified.

Medical DITI's major clinical value is in its high sensitivity to pathology in the vascular, muscular, neural and skeletal systems and as such can contribute to the pathogenesis and diagnosis made by the clinician. Attractive is its completely non-invasive nature and the use of a body-generated signal.

 

 

Application

 

Fig. 1   A left sural muscle injury

 

Clinical uses for DITI include:

·         To define the extent of a lesion of which a diagnosis has previously been made;

·         To localize an abnormal area not previously identified, so further diagnostic tests can be performed;

·         To detect early lesions before they are clinically evident;

·         To monitor the healing process before the patient is returned to work or training.

 

Skin blood flow is under the control of the sympathetic nervous system. In healthy people there is a symmetrical dermal pattern which is consistent and reproducible for any individual. This is recorded in precise detail with a temperature sensitivity of 0.1°C by DITI. The neuro-thermography application of DITI measures the somatic component of the sympathetic response by assessing dermal blood flow. This response appears on DITI as a localized area of altered temperature, up to even 10° C with specific features for each anatomical lesion.

Regular Imaging applications are e.g. early diagnostics of breast cancer and superficial neuro-musculo-skeletal examinations). Further, applications in rheumatology and dermatology and sports medicine.

 

Fig. 2  Functional near-IR optical topography  a). Child seated for a PC screen. b) channel configuration with emitting and receiving channels. c) Time series of relative changes in [oxy-Hb] (red line) and [deoxy-Hb] (green line) at channel 11 over the occipital cortex and at channel 23 over the frontal cortex of a 2-month-old infant. Black and gray bars indicate the test and control trials, respectively. d) response to visual stimulation. Epoch-averaged images of [oxy-Hb] over the occipital and frontal cortex of a 4-month-old infant (S6) are illustrated at 2-s intervals. Scale is relative [oxy-Hb] change from an arbitrary zero baseline. From ref. 1.

 

A limitation of the latter is the restricted depth of imaging. Yet, there are techniques to measure Deep Venous Thrombosis.

Some other physiological activities can also be monitored with thermographic imaging, for instance brain activity, especially in infants as an alternative of the expensive fMRI technique. Actually it is an application in the field of spectroscopy, more precisely a multichannel near-IR optical topography measuring time courses of the levels of oxy-Hb (780 nm) and deoxy-Hb (830 nm) (Fig. 2.

 

 

Literature

1)  http://www.pnas.org/cgi/reprint/100/19/10722

2) http://www.meditherm.com/therm_page1.htm